Localization of repetitive DNA in the chromosomes of Microtus agrestis by means of in situ hybridization |
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Authors: | Frances E Arrighi T C Hsu Priscilla Saunders Grady F Saunders |
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Institution: | (1) Departments of Biology and Developmental Therapeutics, The University of Texas M. D, Anderson Hospital and Tumor Institute at Houston, Houston, Texas;(2) The University of Texas Graduate School of Biomédical Sciences at Houston, Houston, Texas |
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Abstract: | Heterochromatin in the European field vole, Microtus agrestis, was studied using a special staining technique and DNA/RNA in situ hybridization. The heterochromatin composed the proximal 1/4 of the short arm and the entire long arm of the X chromosome, practically the entire Y chromosome and the centromeric areas of the autosomes. By using the DNA/RNA in situ hybridization technique, repeated nucleotide sequences are shown to be in the heterochromatin of the sex chromosomes.Supported in part by Research Grants DRG-1061 and 269 from the Damon Runyon Memorial Fund for Cancer Research, G-373 and G-267 from the Robert A. Welch Foundation. |
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