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| 非洲爪蟾BAFF及其信号通路相关基因的比较生物信息学分析 | |
| 引用本文： | 齐志涛,张启焕,黄贝,王资生,仇明,黄金田,许伟,王爱民.非洲爪蟾BAFF及其信号通路相关基因的比较生物信息学分析[J].生物技术,2011,21(4). |
| 作者姓名： | 齐志涛 张启焕 黄贝 王资生 仇明 黄金田 许伟 王爱民 |
| 作者单位： | 1. 盐城工学院海洋技术系,江苏省沿海池塘养殖生态重点实验室,江苏盐城224051;盐城工学院化学与生物工程学院,生物实验中心,江苏盐城224051 2. 盐城工学院化学与生物工程学院,生物实验中心,江苏盐城224051 3. 中国科学院水生生物研究所,淡水生态与生物技术国家重点实验室,湖北武汉430070 4. 盐城工学院海洋技术系,江苏省沿海池塘养殖生态重点实验室,江苏盐城224051 |
| 基金项目： | 江苏省高校自然科学基金项目，盐城工学院人才引进项目 |
| 摘 要： | 目的:对非洲爪蟾BAFF和BAFF信号通路相关基因进行了分析.方法:采用生物信息学方法对两栖类重要的模式生物-非洲爪蟾的基因组和EST数据库进行分析.结果:非洲爪蟾BAFF cDNA全长为557 bp,编码218个氨基酸.与人BAFF序列相似性为37.5％.该文一共得到了14个BAFF信号通路相关基因.通过与人BAFF信号通路进行比较,对非洲爪蟾这14个BAFF信号通路相关基因进行了分析.结论:BAFF和BAFF信号通路在进化过程中较为保守,这为进一步研究低等脊椎动物BAFF功能和信号通路具有重要的指导作用. |
| 关 键 词： | 非洲爪蟾 BAFF BAFF受体 信号通路 生物信息学 |
A Comparative Bioinformatics Study of BAFF and Genes Involving in BAFF Signaling Pathway of Xenopus tropicalis |
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| QI Zhi-tao,ZHANG Qi-huan,HUANG Bei,WANG Zi-sheng,QIU Ming,HUANG Jin-tian,XU Wei,WANG Ai-min.A Comparative Bioinformatics Study of BAFF and Genes Involving in BAFF Signaling Pathway of Xenopus tropicalis[J].Biotechnology,2011,21(4). | |
| Authors: | QI Zhi-tao ZHANG Qi-huan HUANG Bei WANG Zi-sheng QIU Ming HUANG Jin-tian XU Wei WANG Ai-min |
| Institution: | QI Zhi-tao1,2,ZHANG Qi-huan2,HUANG Bei3,WANG Zi-sheng1,QIU Ming1,HUANG Jin-tian1,XU Wei2,WANG Ai-min1(1.Department of Ocean Technology,Key Laboratory of Aquaculture and Ecology of Coastal Pool of Jiangsu Province,Yancheng Institute of Technology,Yancheng 224051,China,2.Central Laboratory of Biology,Chemical and Biological Engineering College,3.State Key Laboratory of Freshwater Ecology and Biotechnology,Institute of Hydrobiology,Chinese Academy of... |
| Abstract: | Objective:To further understanding the BAFF and genes involving in BAFF signaling.Method:Using bioinformatics method,the genome and EST database of Xenopus tropicalis,an important model of amphibian,were analyzed.Result:The BAFF and genes involving in BAFF signaling pathway were first systemtic analyzed.The Xenopus tropicalis BAFF cDNA is 557 bp in length,encoding 218-aa.Xenopus tropicalis BAFF shared 37.5% identities with human BAFF.Furthermore,there were 14 BAFF signaling-related genes was obtained.Conclu... |
| Keywords: | Xenopus tropicalis BAFF BAFF receptors signaling pathway bioinformatics analysis |
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