A pharmacological approach to first aid treatment for snakebite |
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| Authors: | Saul Megan E Thomas Paul A Dosen Peter J Isbister Geoffrey K O'Leary Margaret A Whyte Ian M McFadden Sally A van Helden Dirk F |
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| Institution: | Department of Nuclear Medicine, John Hunter Hospital, New Lambton, New South Wales, Australia. |
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| Abstract: | Snake venom toxins first transit the lymphatic system before entering the bloodstream. Ointment containing a nitric oxide donor, which impedes the intrinsic lymphatic pump, prolonged lymph transit time in rats and humans and also increased rat survival time after injection of venom. This pharmacological approach should give snakebite victims more time to obtain medical care and antivenom treatment. |
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