Emergence of vancomycin-intermediate <Emphasis Type="Italic">Staphylococcus aureus</Emphasis> from predominant methicillin-resistant <Emphasis Type="Italic">S. aureus</Emphasis> clones in a Korean hospital |
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Authors: | Hwa Yun Cha Hyun Ok Kim Jong Sook Jin Je Chul Lee |
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Institution: | 1.Health and Environment Institute of Daegu,Daegu,Republic of Korea;2.Department of Microbiology,Kyungpook National University School of Medicine,Daegu,Republic of Korea |
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Abstract: | The genetic and epidemiological features of four vancomycin-intermediate Staphylococcus aureus (VISA) isolates obtained from a Korean hospital were evaluated in this study. The VISA isolates were genotyped as sequence
type (ST) 5-staphylococcal cassette chromosome mec (SCCmec) II variant (n=2) and ST239-SCCmec III (n=2), which were derived from the predominant methicillin-resistant S. aureus (MRSA) clones in Korean hospitals. One VISA isolate was acquired during vancomycin treatment, whereas three VISA isolates
were obtained from the patients who had not previously been exposed to glycopeptides. As VISA is likely to arise from the
predominant MRSA clones and may then possibly spread between patients, the emergence of VISA should be monitored with great
care in hospitals. |
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Keywords: | |
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