| 脂质组学研究方法及其应用 |
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| 引用本文： | 王涛,梅旭荣,钟秀丽,李玉中.脂质组学研究方法及其应用[J].植物学通报,2010,45(2):249-257. |
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| 作者姓名： | 王涛 梅旭荣 钟秀丽 李玉中 |
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| 作者单位： | 中国农业科学院农业环境与可持续发展研究所,农业部旱作节水农业重点开放实验室,北京100081 |
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| 基金项目： | 国家自然科学基金，"十一五"国家科技支撑计划 |
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| 摘 要： | 脂质不仅是生物膜的骨架成分和能量贮存物质,越来越多的证据表明,脂质也参与细胞的许多重要功能。脂质组学是代谢组学的一个重要分支,主要研究生物体内所有的脂质分子的特性以及它们在蛋白质表达和基因调控过程中的作用。脂质组学是依赖技术驱动的科学。近年来,随着人们对脂质研究的重视,脂质组学研究方法和策略有了突破性进展,在动物上开发出的脂质组学分析方法已经扩展应用到植物上。该文重点介绍脂质组学的研究方法及其应用,以期推动脂质组学,特别是植物脂质组学的进一步发展。
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| 关 键 词： | 色谱 脂质组学 质谱 代谢组学 软电离 |
The Profiling Method of Lipidomics and Its Applications |
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| Tao Wang,Xurong Mei,Xiuli Zhong,Yuzhong Li Key Laboratory of Dryl, Farming , Water-saving Agriculture,Ministry of Agriculture.The Profiling Method of Lipidomics and Its Applications[J].Chinese Bulletin of Botany,2010,45(2):249-257. |
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| Authors: | Tao Wang Xurong Mei Xiuli Zhong Yuzhong Li Key Laboratory of Dryl Farming Water-saving Agriculture Ministry of Agriculture |
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| Institution: | Tao Wang,Xurong Mei,Xiuli Zhong*,Yuzhong Li Key Laboratory of Dryl, Farming , Water-saving Agriculture,Ministry of Agriculture,Institute of Environment , Sus- tainable Development in Agriculture,The Chinese Academy of Agricultural Sciences,Beijing 100081,China |
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| Abstract: | Lipids provide both the structural basis of the cell membrane and fuel for metabolism. In plants, increasing evidence has demonstrated roles for lipids in cellular processes. As one of the most important branches of metabolomics, lipidomics may be a comprehensive strategy to study the cellular lipidomes and their biological roles in terms of protein expression and gene regulation involved in lipid metabolism and function. Progress in lipidomics has been driven by development in analytical methods and approa... |
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| Keywords: | chromatogram lipidomics mass spectrometry metabolomics soft ionization |
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