毛脉酸模不同器官中几种生物活性物质的含量及生长季节对其的影响

为确定毛脉酸模(Rumex gmelini)最佳药用部位和最佳采收期,从而为新药源开发提供科学依据,我们采用HPLC法和梯度洗脱,研究了一年生和二年生毛脉酸模不同生长发育期、不同器官、组织中7种生物活性成分(白藜芦醇、白藜芦醇苷、大黄酚苷、酸模素、大黄素、大黄酚和大黄素甲醚)的动态分布规律.结果表明毛脉酸模根部含有生物活性成分的种类及含量均多于其他部位,为最佳药用部位.一年生毛脉酸模根部不含有酸模素.二年生毛脉酸模根部含有全部7种生物活性成分,且在8～9月份含量最高,为最佳采收期.

Content of Active Components of Organs of Rumex gmelini and the Influence by Growing Time

To confirm the most appropriate pharmaceutical source and harvest time and provide a scientific basis for exploiting Rumex gmelini, we used HPLC to examine the dynamic distribu- tion of 7 components (resveratrol, polydatin, chrysophanol, chrysophaein, emodin, physcion and musizin) in organs, tissues and development stages of 1- or 2-year-old Rumex gmelini. The kind and content of active components varied in roots as compared with other plant parts, with roots being the most appropriate pharmaceutical source. Musizin was not found in 1-year-old plants. All 7 active components were found in roots of 2-year-old plants, and the content was higher during August and September, so this period is the most appropriate harvest time for R. gmelini.