ATP-dependent proteases in plant mitochondria: What do we know about them today? |
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Authors: | Hanna Janska |
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Institution: | Institute of Biochemistry and Molecular Biology, University of Wroclaw, Przybyszewskiego 63/77, 51-147 Wroclaw, Poland |
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Abstract: | Lon-, Clp- and FtsH-like proteases, members of three families of ATP-dependent proteases derived from bacterial ancestors, have been identified in plant mitochondria. Classifications of mitochondrial-specific paralogues of plant ATP-dependent proteases, based on targeting prediction programs and different experimental methods, are compared. Accumulating evidence points to similarities in the structure and the mechanisms of action used by various ATP-dependent proteases. Therefore, before focusing on plant mitochondrial ATP-dependent proteases, the paper discusses general features of ATP-dependent proteases. To date, information about structure and function of plant mitochondrial Lon-like, Clp-like and FtsH-like proteases is rather scarce, but indicates that these enzymes, like their bacterial and eukaryotic homologues, combine proteolytic and chaperone-like activities to form mitochondrial protein quantity and quality control system in plants. |
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