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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
Authors:Jia Z Shen  Zhixin Qiu  Qiulian Wu  Darren Finlay  Guillermina Garcia  Dahui Sun  Juha Rantala  William Barshop  Jennifer L Hope  Ryan C Gimple  Olle Sangfelt  Linda M Bradley  James Wohlschlegel  Jeremy N Rich  Charles Spruck
Institution:1. Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA;2. Division of Regenerative Medicine, Department of Medicine, Moores Cancer Center and Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA 92037, USA;3. Tumor Microenvironment and Cancer Immunology Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA;4. Histology Core, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA;5. Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2RX, UK;6. Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;7. Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA;8. Department of Cell and Molecular Biology, Karolinska Institute, 171 77 Stockholm, Sweden
Abstract:
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  • Keywords:FBXO44  SUV39H1  repetitive elements  H3K9me3  immunotherapy
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