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Proteogenomic characterization of pancreatic ductal adenocarcinoma
Institution:1. Department of Pathology, Johns Hopkins University, Baltimore, MD 21231, USA;2. Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA;3. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA;4. Department of Medicine, Washington University in St. Louis, St. Louis, MO 631110, USA;5. McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA;6. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA;7. Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA;8. The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA;9. Department of Oncology, Johns Hopkins University, Baltimore, MD 21205, USA;10. Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada;11. Sema4, a Mount Sinai venture, Stamford, CT 06902, USA;12. Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA;13. Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA;14. Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada;15. Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA;16. Van Andel Research Institute, Grand Rapids, MI 49503, USA;17. Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;18. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;19. Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA;20. Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD 20892, USA;21. Departments of Surgery and Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada;22. The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD 21231, USA
Abstract:
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  • Keywords:pancreatic ductal adenocarcinoma  proteogenomics  KRAS  neoplastic cellularity  glycoproteins  kinase inhibitors  immune-cold tumors  endothelial cell  tumor subtyping  CPTAC
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