Further serological analysis of the Qa antigens: Analysis of an anti-H-2.28 serum |
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| Authors: | Lorraine Flaherty Debra Zimmerman Ted H Hansen |
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| Institution: | (1) Division of Laboratories and Research, New York State Department of Health, 12201 Albany, New York;(2) Transplantation Biology Section, Immunology Branch, National Cancer Institute, National Institutes of Health, 20014 Bethesda, Maryland |
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| Abstract: | Further serological analyses of the tissue and strain distributions for the Qa-2 antigens indicate that this locus should be subdivided into two loci,Qa-2 andQa-3. TheQa-2 locus determines a lymphocyte alloantigen which is present predominantly on Thy-1+ cells. The lymphocyte alloantigen determined by theQa-3 locus is more limited in its tissue distribution and appears only on lymph node and splenic lymphocytes. Testing of anti-H-2.28 sera has revealed that at least one anti-H-2.28 serum contains anti-Qa-2 and/or anti-Qa-3 activity. |
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