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MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells

Authors:	Chetty Chandramu Vanamala Sravan K Gondi Christopher S Dinh Dzung H Gujrati Meena Rao Jasti S

Institution:	^a Program of Cancer Biology, Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA ^b Department of Neurosurgery, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA ^c Department of Pathology, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA

Abstract:

Keywords:	MMP-9 matrix metalloproteinase-9 CD44_ECD CD44 extracellular domain CD44_ICD CD44 intracellular domain GBM Glioblastoma hMMP-9 purified human MMP-9 rhCD44 recombinant human CD44 APMA p-aminophenylmercuric acetate HA hyaluronic acid SV scrambled vector IHC immunohistochemical CNS central nervous system ECM Extracellular matrix
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