首页 | 本学科首页   官方微博 | 高级检索  
   检索      


First isolation of Rickettsia monacensis from a patient in South Korea
Authors:Yeon‐Sook Kim  Yeon‐Joo Choi  Kyung‐Min Lee  Kyu‐Joong Ahn  Heung‐Chul Kim  Terry Klein  Ju Jiang  Allen Richards  Kyung‐Hee Park  Won‐Jong Jang
Institution:1. Division of Infectious Diseases, Department of Internal Medicine, Chungnam National University School of Medicine, Munhwa‐ro 282, Jung‐gu, Daejeon 35015;2. Department of Microbiology, Konkuk University College of Medicine, Institute of Biomedical Science Building. Neungdong‐ro 120, Gwangjin‐gu, Seoul 05029;3. International Vaccine Institute, SNU Research Park, Gwanak‐ro 1, Gwanak‐gu, Seoul, 151742;4. Department of Dermatology, Konkuk University College of Medicine, Neungdong‐ro 120‐1, Gwangjin‐gu, Seoul, 05029, South Korea;5. Fifth Medical Detachment, 168th Multifunctional Medical Battalion, 65th Medical Brigade, Unit 15247, APO AP 96205–5247;6. Force Health Protection and Preventive Medicine, 65th Medical Brigate/USAMEDDAC–K, Unit 15281, APO AP 96205–528;7. Department of Viral and Rickettsial Diseases, Naval Medical Research Center, Silver Spring, MD 20910, USA
Abstract:
A Rickettsia sp. was isolated from the blood of a patient with an acute febrile illness using the shell vial technique; the isolate was named CN45Kr and was identified by molecular assay as Rickettsia monacensis , which was first recognized as a pathogen in Spain. Sequencing analysis showed that the gltA sequence of the isolate was identical to that of Rickettsia sp. IRS3. The ompA‐ 5mp fragment sequence showed 100% identity to those of R. monacensis and Rickettsia sp. In56 and ompA‐3pA In56 and 100% identity to that of Rickettsia sp. IRS3. The ompB sequence was found to have 99.9% similarity to that of R. monacensis IrR/Munich. This study confirms the pathogenicity of this agent and provides additional information about its geographic distribution.
Keywords:isolation  Rickettsia monacensis  South Korea  spotted fever group rickettsia
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号