| 猪戊型肝炎病毒防控及研究策略分析 |
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| 引用本文： | 李 震,陆海平,董世娟,朱于敏,于瑞嵩.猪戊型肝炎病毒防控及研究策略分析[J].微生物学通报,2009,36(1):0130-0133. |
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| 作者姓名： | 李 震 陆海平 董世娟 朱于敏 于瑞嵩 |
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| 作者单位： | 1. 上海市农业科学院畜牧兽医研究所,上海,201106;上海市农业遗传育种重点实验室,上海,201106
2. 上海市松江区兽医卫生监督检验所,上海,201611 |
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| 基金项目： | 上海市科委重点科技攻关项目资助(No. 063919121); 上海市科委重大科技攻关项目资助(No. 07dz19508) |
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| 摘 要： | 戊型肝炎为人畜共患病病原, 猪是主要的病毒储库。我国猪场戊肝病毒流行情况复杂, 猪感染率高, 同一地点存在3型或/和4型两种基因型混合污染。病毒存在基因重组和准种现象, 为病毒遗传进化提供了遗传基础。当前猪戊肝感染人的主要媒介为污染的猪肉及其制品, 其他感染机制和途径还有待进一步阐明。应加强对猪HEV与猪场其他流行病原体相互关系的研究, 同时应加强猪HEV相关信息的积累分析包括对猪HEV感染特性和遗传特性进行实时监测, 将猪HEV流行情况纳入兽医公共卫生预警体系, 实现常态跟踪。
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| 关 键 词： | 戊型肝炎 猪 流行状况 防控策略 |
Research and Control Strategy of Swine Hepatitis E Virus in China |
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| LI Zhen,LU Hai-Ping,DONG Shi-Juan,ZHU Yu-Min and YU Rui-Song.Research and Control Strategy of Swine Hepatitis E Virus in China[J].Microbiology,2009,36(1):0130-0133. |
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| Authors: | LI Zhen LU Hai-Ping DONG Shi-Juan ZHU Yu-Min and YU Rui-Song |
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| Institution: | (1. Institute of Animal Sciences and Veterinary Medicine, Shanghai 201106, China) (2. Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, China);Songjiang Institute of Veterinary Hygiene Supervision, Songjiang District, Shanghai 201611, China;(1. Institute of Animal Sciences and Veterinary Medicine, Shanghai 201106, China) (2. Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, China);(1. Institute of Animal Sciences and Veterinary Medicine, Shanghai 201106, China) (2. Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, China);(1. Institute of Animal Sciences and Veterinary Medicine, Shanghai 201106, China) (2. Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, China) |
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| Abstract: | Hepatitis E, a newly emerging zoonotic infectious disease, is of major public health concern worldwide. Its pathogen is hepatitis E virus (HEV), which is in most cases enterically transmitted. Pigs are regarded as the major virus reservoir. The epidemic state of the disease is complicated in China. There exist genotype 4 and/or 3 HEV in pig farms. Gene recombination and quasispecies of HEV is providing genetic foundation to the evolution of the viruses. Consuming contaminated pig meat and organs is the major cause of infection with the zoonotic pathogen. Research is needed to throw light on the relationship of swine HEV with other epidemic pathogens in pig farms. Real time inspection of genetic and pathogenic variation of swine HEV will provide valuable information for taking proper prophylaxis measures. Analysis of epidemic state of swine HEV should be one of the key issues in Veterinary Public Health (VPH) system. |
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| Keywords: | Hepatitis E Pig Epidemic state Control strategy |
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