肠道菌群与疾病关系的研究进展

人类肠道是一个多元化和充满活力的微生态系统,它的结构和功能成为目前生命科学和医学的研究热点。人类肠道拥有100万亿近1 000-1 150种细菌,在这个空间中它们与人类相互作用,对人类健康产生了巨大影响,其中有积极的作用,同时又伴随着潜在的威胁。本文详细论述了国内外关于肠道菌群与疾病关系的研究现状,益生菌对肠道菌群和健康的影响,以及研究肠道菌群的最新方法,为我国开展肠道微生物的研究提供部分参考,同时让人们更加了解肠道微生物对人类健康的影响。

Research on the relation between gastrointestinal microbiota and disease

Human gastrointestinal is a diversified and live microecological system, and a body site of scientific interest. Intestinal tract comprises 100 trillion and nearly 1 000 to 1 150 bacterial phylotypes that interact and influence the health of the human host. The influences could be positive or with potential threats. In this paper, the relationship between gastrointestinal microbiota and diseases, the effect of probiotics on human health, and the new approach of researching on the gastrointestinal microbiota are reviewed to provide references for domestic researchers, and to raise the awareness of general public regarding gastrointestinal health