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Konjac glucomannan hydrolysate: A potential natural coating material for bioactive compounds in spray drying encapsulation
Authors:Supichar Wattanaprasert  Chaleeda Borompichaichartkul  Pilanee Vaithanomsat  George Srzednicki
Institution:1. Program in Biotechnology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand;2. Department of Food Technology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand;3. Kasetsart Agricultural and Agro‐Industrial Improvement Institute, Kasetsart University, Bangkok, Thailand;4. Food Science and Technology, School of Chemical Engineering, University of New South Wales, Sydney, NSW, Australia
Abstract:This research aimed to develop a suitable coating material for encapsulating a plant bioactive compound via spray drying. A suitable process for modifying the rheological property of konjac glucomannan (KGM) solution by enzymatic treatment was developed. A plant bioactive compound, andrographolide, was selected to use as core material. Mannanase (1500 units of enzyme) was used in the treatment of KGM solution. The concentration of KGM solution was varied from 9 to 18% (w/w). It was found that 12% (w/w) was the optimum KGM concentration that could be hydrolyzed to a viscosity of <100 mPa·s. HPLC analysis of hydrolyzed solution found a fair amount of DP4–DP7 oligosaccharides (where DP is degree of polymerization) were obtained. The solution was then used as coating material in spray drying with inlet air temperature of 170°C and outlet air temperature of 85°C. It was found that 12% (w/w) konjac glucomannan hydrolysate (KGMH) was suitable for coating 2% (w/w) andrographolide. Its efficiency of encapsulation was also higher than that of KGMH combined with gamma‐cyclodextrin or beta‐cyclodextrin. This study revealed a great potential of using KGMH solution for pharmaceutical and food industries in the spray drying encapsulation process.
Keywords:Andrographolide  Coating materials  Konjac glucomannan  Spray drying  Viscosity
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