| 角膜上皮细胞代谢的研究进展 |
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| 引用本文： | 马佰凯,何昕,李炜.角膜上皮细胞代谢的研究进展[J].中华细胞与干细胞杂志(电子版),2014(1):58-64. |
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| 作者姓名： | 马佰凯 何昕 李炜 |
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| 作者单位： | [1]厦门大学医学院,厦门361102 [2]皖南医学院 ,厦门361102 [3]福建省眼科与视觉科学重点实验室厦门大学眼科研究所,厦门361102 |
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| 基金项目： | 基金项目：国家重大科学研究计划项目（2013CB967003）;国家自然科学基金面上项目（81270977）;国家卫生和计划生育委员会科研基金项目（WKJ-FJ一26）;福建省高等学校新世纪优秀人才支持计划项目资助 |
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| 摘 要： | 角膜上皮层位于角膜表面，外邻泪膜，内与角膜前弹力层相连。角膜上皮细胞代谢所需营养及氧分主要通过泪膜、房水和角膜缘毛细血管运送。正常的角膜上皮细胞代谢是维持角膜上皮细胞正常增殖与分化状态的关键。角膜上皮细胞代谢异常可导致上皮损伤或变性，是多种角膜疾病的病理基础。本文就近年来关于角膜上皮细胞代谢相关的组织结构、营养来源、细胞增殖分化以及相关疾病的研究进展进行综述。
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| 关 键 词： | 角膜 上皮细胞 代谢 |
Research progress in the metabolism of corneal epithelial cells |
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| Authors: | Ma Baikai He Xin Li Wei |
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| Institution: | ( Medical College of Xiamen University, Xiamen 361102, China) |
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| Abstract: | Corneal epithelium is located in the surface layer of the cornea, with tear film outside and Bowman＇s layer inside. The nutrient and oxygen for the metabolism of corneal epithelial cells is transmitted by tear film, anterior aqueous humor and corneal limbal capillary. Metabolism of the corneal epithelial cells is tightly correlated with its proliferation and differentiation. The abnormal metabolism of corneal epithelial cells can cause epithelial damage or dystrophy, which is the pathological basis of many corneal diseases. This review summarizes recent research progress regarding corneal epithelial cell metabolism related tissue structure, origin of nutrient, cell proliferation and differentiation and diseases related to corneal epithelial cell metabolism. |
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| Keywords: | Cornea Epithelial cells Metabolism |
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