RETRACTED ARTICLE: An analysis of population structure and linkage disequilibrium using multilocus data in 187 maize inbred lines |
| |
Authors: | Chuanxiao Xie Marilyn Warburton Mingshun Li Xinhai Li Muji Xiao Zhuanfang Hao Qi Zhao Shihuang Zhang |
| |
Institution: | (1) National Key Facility of Crop Gene Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, 12 Zhong-guan-cun South St., 100081 Beijing, P.R. China;(2) Applied Biotechnology Center CIMMYT Apdo, Apdo. Postal 6-641, Mexico, D.F., 06600, Mexico;(3) Life School, Beijing Capital Normal University, Beijing, P.R. China |
| |
Abstract: | This study analyzes population structure and linkage disequilibrium (LD) among 187 commonly used Chinese maize inbred lines,
representing the genetic diversity among public, commercial and historically important lines for corn breeding. Seventy SSR
loci, evenly distributed over 10 chromosomes, were assayed for polymorphism. The identified 290 alleles served to estimate
population structure and analyze the genome-wide LD. The population of lines was highly structured, showing 6 subpopulations:
BSSS (American BSSS including Reid), PA (group A germplasm derived from modern U.S. hybrids in China), PB (group B germplasm
derived from modern U.S. hybrid in China), Lan (Lancaster Surecrop), LRC (derivative lines from Lvda Reb Cob, a Chinese landrace)
and SPT (derivative lines from Si-ping-tou, a Chinese landrace). Forty lines, which formerly had an unknown and/or miscellaneous
origin and pedigree record, were assigned to the appropriate group. Relationship estimates based on SSR marker data were quantified
in a Q matrix, and this information will inform breeder’s decisions regarding crosses. Extensive inter- and intra-chromosomal
LD was detected between 70 microsatellite loci for the investigated maize lines (2109 loci pairs in LD with D′ > 0.1 and 93 out of them at P < 0.01).This suggests that rapidly evolving microsatellites may track recent population structure. Interlocus LD decay among
the diverse maize germplasm indicated that association studies in QTLs and/or candidate genes might avoid nonfunctional and
spurious associations since most of the LD blocks were broken between diverse germplasm. The defined population structure
and the LD analysis present the basis for future association mapping.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. |
| |
Keywords: | Association mapping Linkage disequilibrium Maize (Zea mays L ) Population structure |
本文献已被 SpringerLink 等数据库收录! |
|