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Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury |
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| Authors: | Chih-Yen Wang Jen-Kun Chen Yi-Ting Wu May-Jywan Tsai Song-Kun Shyue Chung-Shi Yang Shun-Fen Tzeng |
| Institution: | (1) Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan;(2) Center for Nanomedicine Research, National Health Research Institutes, Zhunan, Taiwan;(3) Academia Sinica, Institute of Biomedical Sciences, Taipei, Taiwan;(4) Graduate Institute of Biomedicine and Biomedical Technology, National Chi-Nan University, Puli, Taiwan |
| Abstract: | BackgroundTraumatic spinal cord injury (SCI) forms a disadvantageous microenvironment for tissue repair at the lesion site. To consider an appropriate time window for giving a promising therapeutic treatment for subacute and chronic SCI, global changes of proteins in the injured center at the longer survival time points after SCI remains to be elucidated. |
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