Developmental biology: vasculogenesis is a wreck without RECK |
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| Authors: | Welm Bryan Mott Joni Werb Zena |
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| Institution: | Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA. bwelm@itsa.ucsf.edu |
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| Abstract: | The unique membrane-associated inhibitor of matrix metalloproteinases, RECK, is required for vascular maturation during embryogenesis. The phenotype of a loss of function mutation of RECK shows the importance of pericellular proteolysis in development. |
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