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Automated Chemical Synthesis of PNA and PNA-DNA Chimera on a Nucleic Acid Synthesizer |
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| Authors: | Ravi Vinayak Alexander C van der Laan Rick Brill Ken Otteson Alex Andrus Esther Kuyl-Yeheskiely |
| Institution: | 1. Applied Biosystems , Perkin Elmer Corporation , 850 Lincoln Centre Drive, Foster City, CA, 94404, USA;2. Leiden Institute of Chemistry, Gorlaeus Laboratories , P.O. Box 9502, 2300, RA, Leiden, The Netherlands |
| Abstract: | Abstract Automated chemical synthesis of PNA and PNA-DNA chimera on a DNA synthesizer using the monomethoxytrityl/acyl protecting group strategy is described. |
| Keywords: | |