Syntheses,Crystal Structures,and Hydrogen Bonding Patterns of 3′-C-Methylenecarboxylic-3′-deoxythymidine and 3′-C-Methyleneamidilylic-3′-deoxythymidine |
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| Authors: | Joong Young Kim Byeang Hyean Kim |
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| Institution: | Department of Chemistry , Center for Biofunctional Molecules, Pohang University of Science and Technology , Pohang, 790-784, Korea |
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| Abstract: | Abstract Thymidine derivatives containing carboxylic acid and amide groups have been synthesized and the hydrogen-bonding patterns of 3′-C-methylenecarboxylic-3′-deoxythymidine 6 and 3′-C-methyleneamidilylic-3′-deoxythymidine 9 have been characterized by using X-ray crystallography. |
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| Keywords: | Bis‐ketol Triesters Prodrugs Triphosphate Didehydrothymidine |
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