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Synthesis and Biophysical Studies of Modified Oligonucleotides Containing Acyclic Amino Alcohol Nucleoside Analogs |
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| Authors: | Kanda S Ramasamy Vesna Stoisavljevic |
| Institution: | Research Division , ICN Pharmaceuticals, Inc. , 3300 Hyland Avenue, Costa Mesa, CA, 92626, USA |
| Abstract: | Abstract Novel serine derivative of thymine was prepared and incorporated into oligonucleotides. These modified oligonucleotides were studied for their binding affinity with complementary DNA/RNA. |
| Keywords: | |