|
|||||
|
|
Synthesis and Analysis of Nucleosides Bearing Pyrrolepolyamide Binding to DNA |
|
| Abstract: | Abstract An efficient synthesis of adenosine bearing pyrrolepolyamide 1 was achieved by coupling of 3 with 2. The CD spectra obtained at several ligand ]/duplex] ratios allowed verification of the formation complex of the DNA duplex d(CGCAAATTGGC)/d(GCCAATTTGCG)] with 1. |
| Keywords: | Nucleoside bearing pyrrolepolyamide DNA interaction CD spectra |