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Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment
Institution:1. Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;2. Center for Genetic Muscle Disorders, The Kennedy Krieger Institute, Baltimore, MD 21205, USA;3. Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;4. Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;5. Biomedical Engineering and Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;6. Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA;7. Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;8. Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218, USA;9. Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD 21201, USA;10. Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, South Korea
Abstract:
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  • Keywords:pluripotent stem cells  skeletal muscle stem cells  quiescent stem cells  mdx mouse  Duchenne muscular dystrophy
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