关联分析在作物种质资源分子评价中的应用

发掘优异基因资源是作物种质资源分子评价的重要部分,对作物育种尤其是分子育种具有非常重要的实践意义。基于连锁不平衡(LD)的关联分析是基因发掘也是等位基因发掘的有效途径。本文系统介绍了关联分析的基本理论、策略、特点及应用现状,并探讨了其在作物种质资源新(等位)基因发掘中的发展趋势及展望。可以预见,与传统QTL作图及功能基因组学相整合的关联分析必将大大加快我国作物种质资源的研究进程,实现我国种质资源优势向基因资源优势的转变。

Application of Association Analysis in Molecular Evaluation of Crop Germplasm Resources

Gene discovery and allele mining are important in molecular evaluation of crop germplasm resources and are of great practical significance in crop breeding,especially in molecular breeding.Linkage disequilibrium(LD)-based association analysis is an effective approach to find new genes and favorable alleles.In this paper comprehensively basic theories,strategies,characteristics and current successful applications of association analysis in crops were reviewed.The trends and prospects of association analysis were also proposed.It is concluded that with the integration of traditional QTL mapping and functional genomics,association analysis will certainly accelerate the molecular evaluation of crop germplasm resources.