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Metastatic small cell lung cancer causing biliary obstruction
Authors:Maki Obara  Hiroaki Satoh  Yuko T Yamashita  Hiroshi Kamma  Morio Ohtsuka  Shizuo Hasegawa and Kazuo Orii
Institution:(1) Department of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, 305-8575 Tsukuba City, Ibaraki, Japan;(2) Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Japan;(3) Department of Surgery, Ogawa Kokuho Hospital, Japan
Abstract:We report a case with metastatic small cell lung cancer which first manifested with biliary obstruction due to metastasis. Prognosis of patients presenting with jaundice due to hepatic parenchyma involvement is thought to be poor. However, the patient was successfully treated with percutaneous transhepatic biliary drainage and combination chemotherapy with reduced dosage. We believe this to be the first such case report, despite the frequency of metastasis to the liver from small cell lung cancer.
Keywords:small cell lung cancer  liver metastasis  jaundice
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