Comparison of CRISPR/Cas and Argonaute for nucleic acid tests |
| |
| Institution: | 1. State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China;2. College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China;3. Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, Tianjin University of Science and Technology, Tianjin 300457, China;4. National and Local United Engineering Lab of Metabolic Control Fermentation Technology, Tianjin University of Science and Technology, Tianjin 300457, China;5. China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin University of Science and Technology, Tianjin 300457, China;6. College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China;7. Division of Pharmacy and Optometry, University of Manchester, Oxford Road, Manchester M13 9PL, UK |
| |
| Abstract: | Guided, programmable, and target-activated nucleases, exemplified by Cas in the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) system and Argonaute (Ago), are emerging as a new generation of nucleic acid tests (NATs). A specific approach for comparison of these two nucleases side by side in terms of similarities, differences, and complementarities is instrumental for the sensible design of novel NATs. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
