Proteomics of multiprotein complexes: answering fundamental questions in neuroscience |
| |
| Institution: | 1. Biochemie Intrazellulärer Transportprozesse, Ruhr-Universität Bochum, 44801 Bochum, Germany;2. Biomedizinische Forschung, Leibniz-Insitute for Analytische Wissenschaften – ISAS e.V. – (ISAS e.V.), 44139 Dortmund, Germany;3. Systembiochemie, Ruhr-Universität Bochum, 44801 Bochum, Germany;4. Functional Proteomics, Albert-Ludwigs-Universität Freiburg, 79104 Freiburg, Germany;1. Department of Biology, Faculty of Sciences, Kyushu University, 744 Motooka Nishi-ku, Fukuoka 819-0395, Japan;2. Division of Organelle Homeostasis, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan |
| |
| Abstract: | Proteomics tools offer new ways to analyse networks of proteins that control important neurobiological phenomena such as learning and memory. In this review, we discuss how a combined proteomic, pharmacological and genetic approach reveals that multiprotein complexes process neural information and encode memories. Simultaneous analysis of multiple proteins enables the development of new concepts and approaches for neuroscience research. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
