A second-generation linkage map of the sheep genome |
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| Authors: | Maurico J de Gortari Brad A Freking Rachel P Cuthbertson Steven M Kappes John W Keele Roger T Stone Kreg A Leymaster Ken G Dodds Allan M Crawford Craig W Beattie |
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| Institution: | (1) USDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, Nebraska 68933, USA, US;(2) AgResearch Molecular Biology Unit, Otago University, Biochemistry Dept., Dunedin, New Zealand, NZ;(3) AgResearch Invermay Agricultural Centre, Private Bag 50034, Mosgiel, New Zealand, NZ |
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| Abstract: | A genetic map of Ovis aries (haploid n = 27) was developed with 519 markers (504 microsatellites) spanning ∼3063 cM in 26 autosomal linkage groups and
127 cM (female specific) of the X Chromosome (Chr). Genotypic data were merged from the IMF flock (Crawford et al., Genetics
140, 703, 1995) and the USDA mapping flock. Seventy-three percent (370/504) of the microsatellite markers on the map are common
to the USDA-ARS MARC cattle linkage map, with 27 of the common markers derived from sheep. The number of common markers per
homologous linkage group ranges from 5 to 22 and spans a total of 2866 cM (sex average) in sheep and 2817 cM in cattle. Marker
order within a linkage group was consistent between the two species with limited exceptions. The reported translocation between
the telomeric end of bovine Chr 9 (BTA 9) and BTA 14 to form ovine Chr 9 is represented by a 15-cM region containing 5 common
markers. The significant genomic conservation of marker order will allow use of linkage maps in both species to facilitate
the search for quantitative trait loci (QTLs) in cattle and sheep.
Received: 20 September 1992 / Accepted: 18 November 1997 |
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