Effect of selenium in recovery of immunity damaged by H2O2 and60Co radiation |
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| Authors: | Enjie Sun Huibi Xu Qiong Liu Jingyan Zhou Ping Zuo Junjian Wang |
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| Institution: | (1) Department of Chemistry, Huazhong University of Science and Technology, 430074 Wuhan, People's Republic of China;(2) Department of Material Engineering, Huazhong University of Science and Technology, 430074 Wuhan, People's Republic of China;(3) Department of Biological and Medical Engineering, Huazhong University of Science and Technology, 430074 Wuhan, People's Republic of China |
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| Abstract: | Con A stimulated lymphocytes proliferation was measured as 3H]thymidine incorporation and IgG was quantified by single radial immunodiffusion to study recovering or protecting effect
of selenium (Se) on immunity attacked by exogenous active oxygen species, H2O2 and60Co-radiation, respectively. Lipid peroxidation was also determined to observe the relation between antioxidation ability and
protecting ability of Se. It was found that H2O2 injured lymphocytes immunocompetence deeply and60Co-radiation decreased immune response capacity greatly, but that administration of Se counteracts this damage. The antioxidative
ability of Se was correlated with its protecting ability. |
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| Keywords: | Selenium H2O2 60Co radiation |
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