Selenium in serum and whole blood in patients with surgical interventions |
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Authors: | K Winnefeld H Dawczynski W Schirrmeister G Adam U Friedrich S Hein |
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Institution: | (1) Surgical Clinic of Friedrich Schiller University, Jena, Germany;(2) Clinic of Anaesthesiology and Intensive Medicine of Friedrich Schiller University, Jena, Germany |
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Abstract: | Selenium values of serum and whole blood were determined for two groups of patients undergoing large surgical interventions
(e.g., gastrectomy) and receiving a total parenteral nutrition (TPN). All patients showed low selenium values at the beginning
of TPN. The first group received a supplementation of selenium, and it was established that selenium levels normalized after
6–7 d. The balances of selenium turned out to be positive in all cases. The second group, which was not administered selenium
supplementation, showed significantly lower values of selenium. It can, therefore, be concluded that a substitution of selenium
prior to large surgical interventions following TPN clearly helps patients combat the increase in the oxidant stress reactions. |
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Keywords: | Gastrectomy TPN selenium serum whole blood supplementation oxidant stress |
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