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Selenium status of healthy immigrant parisian preschool children |
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| Authors: | Abdellatif Chakar Ridha Mokni Philippe Chappuis Jean-Louis Mahu Philip A Walravens Fanny Bleiberg-Daniel Patrice Therond Jean Navarro Daniel Lemonnier |
| Institution: | 1. U 1 INSERM, H?pital Bichat, 46, rue Henri Huchard, 75877, Paris Cedex 18 2. Laboratoire de biochimie, H?pital Lariboisière, 2, rue Ambroise Paré, 75010, Paris 3. Laboratoire de biochimie A, H?pital Robert Debré, 48 boulevard Sérurier, 75019, Paris 4. Service de Gastro-entérologie et Nutrition Pédiatrique, H?pital Robert Debré, 48 boulevard Sérurier, 75019, Paris |
| Abstract: | Plasma selenium (Se) concentration and erythrocyte glutathione peroxidase activity (GPx) were assessed in a population of healthy preschool children two to five years old, residing in the city of Paris. In the 118 subjects, mean (±SD) plasma Se concentration was 62.10 ±13.96 μg/L, and mean GPx activity was 23.58±8.52 U/g Hb. Mean plasma Se of male children was significantly (p=0.001) higher (12%) than levels of girls. Plasma selenium levels were not correlated with erythrocyte GPx activity. Children from Mediterranean origin had a slightly lower erythrocyte GPx activity (p<0.05) than children from other regions. Mean plasma Se concentration of this group corresponded to the lower limit of intervals, which characterizes geographical regions of intermediate selenium concentrations. |
| Keywords: | Selenium plasma glutathione peroxidase erythrocyte selenium status healthy preschool children polarized Zeeman-effect atomic absorption spectrometry sex age ethnic variation |
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