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Concentration of 17 trace elements in serum and whole blood of plains viscachas (Lagostomus maximus) by ICP-MS, their reference ranges, and their relation to cataract
Authors:Forrer R  Wenker C H  Gautschi K  Lutz H
Institution:(1) Clinical Laboratory, Department of Internal Veterinary Medicine, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland;(2) Division of Zoo Animals and Exotic Pets, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland
Abstract:The reference ranges of the trace elements Al, As, Be, B, Cd, Co, Cu, Fe, Mn, Mo, Ni, Pb, Li, Rb, Se, Sr, and Zn were determined by inductively coupled plasma-mass spectrometry (ICP-MS) in sera of a group of free-ranging plains viscachas of the pampa grasslands of Argentina. The values were compared with those of a small group of captive plains viscachas of the Zurich Zoo with diabetes and bilateral cataracts. In addition, a method for digestion of whole-blood samples is described for the trace element determination. Significant differences in the concentration of trace elements in the two groups of animals are discussed. No correlation was found between the levels of selenium and of other trace elements compared to the formation of cataracts.
Keywords:Trace elements  plains viscacha (lagostomus maximus)            cataract  diabetes  serum  whole blood  reference ranges  ICP-MS  aluminum  arsenic  beryllium  boron  cadmium  cobalt  copper  iron  manganese  molybdenum  nickel  lead  lithium  rubidium  selenium  strontium  zinc
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