| 损毁或刺激垂体和下丘脑弓状核对大鼠痛觉调制的影响 |
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| 引用本文： | 陈起亮,李金华.损毁或刺激垂体和下丘脑弓状核对大鼠痛觉调制的影响[J].生理学报,1995,47(5):505-509. |
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| 作者姓名： | 陈起亮 李金华 |
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| 作者单位： | 苏州医学院生理学教研室，苏州医学院神经生物学研究室 |
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| 摘 要： | 用局限性损毁和刺激垂体的方法，观察了垂体与下丘脑弓状核（ＡＲＣ）在痛觉调制中的关系。实验结果表明，损毁垂体中间叶和前叶能降低基础痛阈，取消刺激ＡＲＣ即刻出现的镇痛作用。刺激垂体的相同部位能提高基础痛阈，并出现有一定潜伏期的镇痛作用，这个镇痛作用能被损毁ＡＲＣ所阻断。
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| 关 键 词： | 痛觉调制 损毁 刺激 垂体 下丘脑 弓状核 |
EFFECTS OF LESION OR STIMULATION OF PITUITARY GLAND AND HYPOTHALAMIC ARCUATE NUCLEUS ON PAIN MODULATION IN RATS |
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| CHEN QI-LIANG, LI JIN-HUA, ZHOU ZHI-JING,AND YIN, QI-ZHANG.EFFECTS OF LESION OR STIMULATION OF PITUITARY GLAND AND HYPOTHALAMIC ARCUATE NUCLEUS ON PAIN MODULATION IN RATS[J].Acta Physiologica Sinica,1995,47(5):505-509. |
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| Authors: | CHEN QI-LIANG LI JIN-HUA ZHOU ZHI-JING AND YIN QI-ZHANG |
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| Abstract: | Relationship between pituitary gland and hypothalamic arcuate nucleus (ARC) in the modulation of pain threshold was investigated in Wistar rats with method of focal lesion and stimulation of pituitary gland. Experimental results indicated that electrolytic lesion of the pituitary intermediate and anterior lobes resulted in a decrease of pain threshold and disappearance of the analgesia immediately produced by ARC stimulation. Stimulation of the same area of pituitary gland could induce a delayed analgesia,which could be blocked by ARC lesion. |
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| Keywords: | lesion stimulation pituitary gland hypothalamic arcuate nucleus pain threshold pain modulation |
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