| 成年人脂肪体重、去脂体重和肺通气功能的关系 |
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| 引用本文： | 冯逵,陈莉,祖淑玉,韩少梅,朱广瑾.成年人脂肪体重、去脂体重和肺通气功能的关系[J].生理学报,2010(2). |
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| 作者姓名： | 冯逵 陈莉 祖淑玉 韩少梅 朱广瑾 |
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| 作者单位： | 中国医学科学院基础医学研究所、北京协和医学院基础学院生理与病理生理学系;中国医学科学院基础医学研究所、北京协和医学院基础学院流行病学与统计学系; |
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| 基金项目： | supported by Key Basic Research Program of Ministry of Science and Technology of China (No. FY110300) |
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| 摘 要： | 本文旨在研究分析成年人去脂体重(fat free mass,FFM)、脂肪体重(fat mass,FM)和肺通气功能的关系。随机抽取黑龙江省部分地区19~81岁健康成年人群1307人(男性372人,女性935人),测量身高、体重,采用身体成分仪和肺功能仪分别检测FFM、FM和肺通气功能,并采用Pearson相关分析、独立样本t检验和多元逐步回归等统计学方法分析FFM、FM和肺通气功能的关系。结果显示,无论性别,年龄均与脂肪体重指数(FM index,FMI)呈正相关(P0.001),去脂体重指数(FFM index,FFMI)和用力肺活量(forced vital capacity,FVC)、用力呼气一秒量(forced expiratory volume in one second,FEV1)、最高呼气流量(peak expiratory flow,PEF)、用力呼出25%肺活量时呼气流量(forced expiratory flow at25%of forcedvital capacity,FEF25%)均呈正相关(P0.01),FMI和FVC、FEV1、FEF75%呈负相关(P0.05)。男性FMI和最大呼气中段流量(maximal mid-expiratory flow,MMEF)呈负相关(P0.05)。无论性别,FFMI对于FVC作用大于FMI,而对于FEV1,男性FMI作用大于FFMI,女性则反之。无论性别,FFMI升高,PEF和FEF25%也升高,而FMI对二者无作用。无论性别,FMI升高,FEF75%降低,而FFMI对其无作用。FMI升高,男性MMEF降低,女性无明显改变。本研究结果表明,FFM和FM均是影响肺通气功能的独立因素,反映骨骼肌力的FFM与肺通气功能呈正相关,FM与肺通气功能呈负相关。FFM和FM对肺通气功能作用大小存在差别。
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| 关 键 词： | 身体成分 用力呼气流量 用力肺活量 |
Fat mass and fat free mass on ventilatory function in adults |
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| FENG Kui,CHEN Li,ZU Shu-Yu,HAN Shao-Mei,ZHU Guang-Jin.Fat mass and fat free mass on ventilatory function in adults[J].Acta Physiologica Sinica,2010(2). |
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| Authors: | FENG Kui CHEN Li ZU Shu-Yu HAN Shao-Mei ZHU Guang-Jin |
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| Institution: | FENG Kui1,CHEN Li1,ZU Shu-Yu1,HAN Shao-Mei2,ZHU Guang-Jin1,1Department of Physiology , Pathophysiology,2Department of Epidemiology , Statistics,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100005,China |
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| Abstract: | This study is designed to probe for the effects of fat mass (FM) and fat free mass (FFM) on ventilatory function in adults.1 307 healthy adults (372 males and 935 females) were selected from some localities of Heilongjiang province through random sampling by means of questionnaire and physical examination and measured for height,weight,waist to hip ratio (WHR),FM,FFM and ventilatory function.The data were analyzed by means of Pearson correlation analysis,independent-samples t test and multi-factors regressi... |
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| Keywords: | body composition forced expiratory flow rates forced vital capacity |
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