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离体心肌“生理性”收缩的计算机伺服系统
引用本文:邹沙舟,李云霞.离体心肌“生理性”收缩的计算机伺服系统[J].生理学报,1992,44(4):420-425.
作者姓名:邹沙舟  李云霞
作者单位:湖南医科大学心血管生理研究室,湖南医科大学心血管生理研究室 长沙 410078,长沙 410078
基金项目:国家自然科学基金(No.3870185)
摘    要:扩充了A/D接口的Z-80微机和编制的软件,与肌力计和力位移双态换能器组成伺服系统,可以自动控制换能器金属杆的工作状态和“后负荷”水平,使离体心肌产生时相顺序类同于射血心室的四个时相“生理性”收缩,从而获得心肌的张力长度关系、作功量等心肌力学信息,并可同步观察收缩末期张力长度关系和张力速度关系。

关 键 词:微机伺服系统  生理性收缩  心肌

Use of a computer-controlled servo system to produce "ephysiological" contraction of isolated rat papillary muscle]
ZOU SHA-ZHOU,LI YUN-XIA Laboratory of Cardiovascular physiology,Hunan Medical Unicersity,Changsha.Use of a computer-controlled servo system to produce "ephysiological" contraction of isolated rat papillary muscle][J].Acta Physiologica Sinica,1992,44(4):420-425.
Authors:ZOU SHA-ZHOU  LI YUN-XIA Laboratory of Cardiovascular physiology  Hunan Medical Unicersity  Changsha
Institution:Laboratory of Cardiovascular Physiology, Hunan Medical University, Changsa.
Abstract:A computer-controlled servo system consisting of an ergometer with a force-displacement dual mode transducer, a Z-80 single-board microcomputer and adesigned software was constructed. This servo system can be used to generatephysiological contractio. in isolated rat papillary muscle, in which the muscle wentthrough a complete 4-phase cycle of force and length changes, similar to those un-dergone by muscle fibers in the beating heart during the cardiac cycle. This system is being used to investigate the tension-length relation and the net-work of isolated myocardium as well as the end-systolic tension-length relation andthe force-velocity relation simultaneously.
Keywords:microcomputer servo control system  physiological contration  isolated rat
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