首页 | 本学科首页   官方微博 | 高级检索  
   检索      

胎盘发生过程中的细胞凋亡
作者姓名:Gao F  Fu GQ  Ding F  Liu YX
作者单位:1. 中国科学院动物研究所生殖生物学国家重点实验室,北京 100080
2. 中国科学院动物研究所生殖生物学国家重点实验室,北京,100080
基金项目:This work was supported by WHO/Rockefeller Foundation Network Project, the National "973” Project NSFC (39970284)b and Zhi Shi Chuang-Xin Programs of Chinese Academy of Sciences.
摘    要:细胞凋亡是一种正常的生理现象,在胚泡着床过程中,伴随有大量细胞凋亡。研究表明,胎盘发生过程中的细胞凋亡,对调控子宫内膜基质细胞的蜕膜化和滋养层细胞的浸润以形成胎盘具有重要意义;另外,由Fas/FasL系统介导的细胞凋亡可能与母体对胎儿的免疫耐受性有关。本文主要评述细胞凋亡的一般通路以及胎盘发生过程中细胞凋亡的调控。

关 键 词:细胞凋亡  胎盘发生  免疫耐受  Fas/FasL
修稿时间:2001年3月15日

Apoptosis during placentation
Gao F,Fu GQ,Ding F,Liu YX.Apoptosis during placentation[J].Acta Physiologica Sinica,2001,53(6):409-413.
Authors:Gao F  Fu G Q  Ding F  Liu Y X
Institution:State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, Liuyx@panda.ioz.ac.cn
Abstract:Apoptosis is a normal physiological phenomenon. During the process of implantation, there are a large number of cells at the implantation site undergoing apoptosis, which has been suggested to play an important role in the regulation of endometrium decidulization and trophoblast invasion. Apoptosis mediated by Fas/FasL system may also be associated with maternal immunotolerance to the fetus. In this review, the common pathway of apoptosis and the regulation in the placenta are described.
Keywords:apoptosis  placentation  immunotolerance  Fas/FasL  
本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号