| 强噪声暴露后听觉脑干电反应及皮层电反应的变化 |
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| 引用本文： | 魏保龄,汤浩.强噪声暴露后听觉脑干电反应及皮层电反应的变化[J].生理学报,1994,46(6):553-560. |
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| 作者姓名： | 魏保龄 汤浩 |
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| 作者单位： | 中国医科大学听觉研究室 |
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| 摘 要： | 为了观察噪声作用豚鼠后，在暂时性或移和永久性阈移期间，听觉末梢和听觉各级中枢电反庆的变化规律，我们进行了６２ｄ的测定。听神经电反应振幅减小２９％（Ｐ＜０．０５），耳蜗核电反应振幅减小２８％（Ｐ＜０．０５），上橄榄核电反应反而增加２１％（Ｐ＜０．０５），中脑下丘的电反应振幅进而增大３７％（Ｐ＜０．０５），听觉皮层电反应振幅却意外地增加１３１％（Ｐ＜０．００１）。这说明强噪声（１２５ｄＢ １５０ｍｉｎ
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| 关 键 词： | 听觉脑干电反应 噪声 皮层电反应 听觉 |
CHANGES OF AUDITORY BRAINSTEM RESPONSE AND AUDITORY CORTEX RESPONSE AFTER EXPOSURE TO INTENSIVE NOISE |
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| WEI BAO-LING,TANG HAO,KANG JIAN,QU FEI AND NIE ZHI-WEI.CHANGES OF AUDITORY BRAINSTEM RESPONSE AND AUDITORY CORTEX RESPONSE AFTER EXPOSURE TO INTENSIVE NOISE[J].Acta Physiologica Sinica,1994,46(6):553-560. |
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| Authors: | WEI BAO-LING TANG HAO KANG JIAN QU FEI AND NIE ZHI-WEI |
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| Abstract: | Auditory brainstem response and auditory cortex response were recorded repeatedly in 35 guinea pigs after exposure to intensive white noise(125 dB,150 min.)for 62d.the amplitude of evoked potential of acoustic nerve was decreased by 29%(P<0.05),of the cochlear nuclei by 28%(PRO.05).Hower,the amplitude of response of superior olives nuclei was ificreased by 21%(PRO.05),of the inferior colliculi by 37%(P<0.05),of the conical evoked response by 131%(P<0.001).The results indicate that the amplitudes of auditory evoked potential showed a centripital augmentation after exposure to intensive noise.The centripital augmentation was observed not only during the period of the temporary threshold shift(TTS)but also during that of the permanent threshold shift(PTS). |
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| Keywords: | auditory brainstem response auditory middle latency response noise |
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