Coprinol, a new antibiotic cuparane from a Coprinus species |
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| Authors: | Johansson M Sterner O Labischinski H Anke T |
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| Institution: | Division of Organic Chemistry 2, Chemical Center, University of Lund, Sweden. |
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| Abstract: | Coprinol, a new antibacterial cuparane, was isolated from fermentations of a Coprinus sp. Its biological activities were investigated and its structure was elucidated by spectroscopic methods. The new antibiotic exhibited activitiy against multidrug-resistant Gram-positive bacteria in vitro. Two derivatives were synthesized and their activities compared to the parent compound. |
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