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Imatinib mesylate affects extracellular ATP catabolism and expression of NTPDases in a chronic myeloid leukemia cell line |
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| Authors: | Willig Julia Biz Vianna Débora Renz Barreto Beckenkamp Aline Beckenkamp Liziane Raquel Sévigny Jean Wink Márcia Rosângela Buffon Andréia Pilger Diogo André |
| Institution: | 1.Faculty of Farmacy, Program for Post-graduation in Pharmaceutical Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil ;2.Laboratory of Biochemical and Cytological Analyses, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Bairro Santana, Porto Alegre, Rio Grande do Sul, CEP 90610-000, Brazil ;3.Laboratory of Cell Biology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil ;4.Department of Microbiology-Infectiology and Immunology, Faculty of Medicine, Université Laval, Quebec, QC, Canada ;5.Centre de Recherche du CHU de Québec, Université Laval, Quebec, QC, Canada ; |
| Abstract: | Purinergic Signalling - Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm, characterized by the occurrence of the t(9;22)(q34;q11) translocation. First-line therapy for CML consists... |
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