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尿蛋白定性与定量检测结果的差异性和相关性分析
引用本文:周琼芝,王玉明,郭翀,刘华,周胤余.尿蛋白定性与定量检测结果的差异性和相关性分析[J].生物磁学,2014(4):744-747.
作者姓名:周琼芝  王玉明  郭翀  刘华  周胤余
作者单位:[1]昆明医科大学,云南昆明650032 [2]昆明医科大学第一附属医院检验科,云南昆明650032
摘    要:目的:探讨尿液干化学法及免疫透射比浊法检测尿白蛋白结果的差异性及相关性。方法:对514例住院患者随机尿标本进行尿液干化学法及免疫透射比浊法尿蛋白的检测。结果:尿液干化学法阳性率为82.1%,免疫透射比浊法阳性率为72.8%。两种方法检测结果均为阴性标本的符合率为98.9%,为(±)的标本二者符合率为69.7%,为㈩的标本二者符合率为75.6%,为(++)的标本二者符合率为67.2%,为(卅)标本中二者符合率为42.5%,为(++H)标本二者的符合率为37.5%。两种方法的检测结果有显著性差异(P〈O.05);UmAlb/Ucr、NAG、和NAG/Ucr与UmAlb具有显著相关(P〈0.05),且UmAlb/Ucr与UmAlb的相关性最高。两种方法所得等级结果比较,++~卅之间差异有统计学意义(P〈0.05),-~±、±~+、+~++、+++~++++之间差异均无统计学意义(P〉0.05)。结论:尿蛋白定性与定量检测结果存在显著性差异,而UmAlb/Ucr与UmAlb相关性较高。在泌尿系统疾病的诊断中,检测尿中UmAlb比尿常规更有意义。

关 键 词:尿微量白蛋白  尿液干化学  免疫透射比浊

Analysis of the Difference and Correlation between the Qualitative and Quantitative Test Results for Urinary Protein
ZHOU Qiong-zhi,WANG Yu-ming,GUO Chong,LIU Hua,ZHOU Yin-yu.Analysis of the Difference and Correlation between the Qualitative and Quantitative Test Results for Urinary Protein[J].Biomagnetism,2014(4):744-747.
Authors:ZHOU Qiong-zhi  WANG Yu-ming  GUO Chong  LIU Hua  ZHOU Yin-yu
Institution:1 Kunming medical university, Yurmun, Kunming, 650032, China; 2 Department of clinical laboratory, The first affiliated hospital of Kunming medical university, Yunnun, Kunming, 650032, China)
Abstract:Objective: To explore the difference and correlation of microalbuminuria test results between the urine dry chemical method and immune transmission turbidity. Methods: 514 cases of hospitalized patients with random urine specimen were tested by the microalbuminuria of urine analyzer and immune transmission turbidimetry. Results: The test positive rate of urine dry chemistry method was 82.1%, while the test positive rate of immune transmission turbidimetry was 72.8%. The coincidence rate of two methods in which the test results were negative specimens was 98.9%, For (+) specimens, the coincidence rate was 69.7%, for (+) specimens, the coincidence rate was 75.6%, for (+ +) specimens the coincidence rate was 67.2%, for (+ + +) specimens the coincidence rate was 42.5%, for (+ + + +) specimens the coincidence rate was 37.5%. Significant difference was found between the two methods test results (P〈0.05); UmAlb/Ucr, NAG, NAG/Ucr had significant correlations with UmAlb (P 〈0.05), and the highest correlation was with UmAlb/Ucr. For the rank results of two methods, ++ -+++ (P 〈0.05) difference was statistically significant, the range of--+ , + - +, +--++, +++- ++++ were not statistically significant. Conclusion: The results of qualitative and quantitative detection of urinary protein were significantly different, and the correlation between UmAlb/Ucr and UmAlb was very high, the urine UmAlb was more meaningful than urine routine in the diagnosis of urinary system disease.
Keywords:UmAlb  Urine dry chemical  Immune transmission turbidity
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