吲哚氰绿排泄试验评价肝储备功能与拔管时问的研究

目的：术前评估肝硬化患者肝脏储备功能,及其与患者拔管时间及改良OAA/S评分的关系。方法：对60例肝硬化失代偿患者术前行吲哚氰绿排泄试验。将患者分为三组：按吲哚氰绿15min储留率（ICGR15）将患者分为两组I1组,I2组,另30例肝功能正常患者为对照组（C组）。观测ICGR15与患者拔管时间及改良OAA/S评分的关系。结果：拔管时间I1组与I2组均明显长于C组（P〈0.05或P〈0.01）;发生呕吐,烦躁者I1组与I2组均明显多于C组（P〈0.05或P〈0.01）,OAA/S评分〉3分者I1组与I2组均多于C组,但无统计学意义。结论：ICGR15对于判断肝硬化患者围术期拔管的时间具有一定的参考价值。

Evaluation of liver functional reserve and extubation time by indocyanine green excretion test

Objective：To evaluate the liver reserve function in patients with cirrhosis and its relation to extubation time in patients and modified OAA/S score.Methods：Sixty patients with decompensatively stative hepatic cir-rhosis scheduled to received devascularization in combination with splenectomy,the ICG excretion test were performed one day before operation.The patients were divided into three groups：group I1（n=30,20〈ICGR15 25）（ICGR15：indocyanine green retention at fif-teen minutes）;group I2（n=30,ICGR15〉 25）;groupC（n=30,control group）.ICGR15 and extubation time were observed and improve-ment in OAA/S score.Result：I1 group and I2 group extubation time were significantly longer than group C（P〈0.05 or P〈0.01）;vomit-ing,irritability are I1 group and I2 group were significantly more than C group（P〈0.05 or P〈0.01）;OAA/S score〉3 were I1 and I2 groups were more than group C,but not statistically significant.Conclusion：ICGR15 may play a role estimate extubation time of the pa-tient with hepatic cirrhosis.