信息管理系统对医院药品管理规范化的作用及意义

目的：评价血清中甲状腺特异性抗体的存在对乳腺癌患病风险的影响，为评估乳腺癌的预后及制定治疗方案提供理论依据。方法：计算机检索Medline（1950~2012）、EMBASE（1949~2012）、Pubmed（1946~2012）、Current Contents Connect（1998~2012）和Google Scholar（1992~2012）等英文数据库。收集关于甲状腺特异性抗体与乳腺癌（Breast Cancer, BC）相关性分析的横断面研究或队列研究。按Cochrane 系统评价方法，评价所纳入研究的文献质量，有效数据采用RevMan5.2 软件进行系统评价。结果：最终纳入6 项研究，共计6945 例患者。系统评价结果显示：乳腺癌的风险会随血清中甲状腺特异性抗体（包括甲状腺过氧化物酶抗体anti-TPO 和甲状腺球蛋白抗体anti-TG）的存在而增加（anti-TPO OR 2.51，95%CI： 1.94-3.25；anti-TG 2.67, 95%CI： 1.65-4.33）。结论：乳腺癌的风险会随血清中甲状腺特异性抗体的存在而增加，甲状腺特异性抗体可能为乳腺癌预后的评估以及治疗原则的制定提供理论基础。

Effects and Significance of Hospital Information System on the Standardization of Pharmaceutical Management

Objective： The hospital information system has been applied widely in many hospitals. It is suggested that the hospital information system could improve the quality and efficiency of medical works as well as the clinical level of hospital. The hospital infor- mation system also plays an essential role in the standardization of pharmaceutical management. This article is written to explore the ef- fects and significance of hospital information system on the management of drugs in order to provide an available method for hospital management. Methods： The purchase, receiving, price, sales and inventory etc. of drugs were standardized by means of hospital informa- tion system. Then the situations of dispensing velocity, pricing standard, drug management, counting efficiency, etc were observed and compared before and after the application of information system of hospital management. Results： After the application of information management, the time for drugs＇ distribution and inventory were significantly shorter, the accuracy of pricing was obviously improved, the waste of drugs and the delay of purchasing were reduced and the management and supervision for special drugs were enhanced signif- icantly （P〈0.05）. Conclusions： It is indicated that the application of hospital information system on the medication management could be an effective and significant method of standardizing the process of medication, improve the quality and efficiency of clinical affairs, and provide a better medical service for patients that help the hospital to make overall modemization.