药物涂层支架与金属裸支架治疗ST段抬高型心肌梗死的临床价值比较

目的：评价药物涂层支架（DES）与金属裸支架（BMS）在急性心肌梗死患者中应用的安全性和有效性。方法：选择2003年1月-2010年12月，在我院确诊的急性sT段抬高型心肌梗死（STEMI）167例患者，其中使用BMS65例，DES102例。对比分析两组患者住院期间和出院后1年内的主要心血管或脑血管事件（MAACE）的发生情况及支架内血栓形成的发生率。结果：至随访结束，BMS组有1例患者猝死，5例出现复发心绞痛。DES组有1例突发急性左心衰后死亡，1例复发心绞痛和1例发生亚急性支架内血栓。结论：DES应用于STEMI具有较好的安全性，其术后MAACE发生率较BMS低。

Comparison of the Clinical Value of Drug-eluting Stent with Bare Metal Stent in the Treatment of ST-segment Elevation Myocardial Infarction

Objective： To evaluate and contrast the safety and efficacy of drug-eluting stem （DES） and bare metal stents （BMS） in patients with acute myocardial infarction. Methods： 167 cases of patients diagnosed with ST-segment elevation myocardial infarction （STEMI） in our hospital were selected from January 2003 to December 2010, who included 65 cases implanted with BMS and 102 cases implanted with DES. The occurrence of major cardiovascular or cerebrovascular events （MAACE） conditions and stent thrombosis incidence of two groups were analyzed retrospectively and compared respectively during hospitalization and 1 year after discharge. Results： To the end of follow-up, BMS group had one case of sudden death and five cases of recurrent angina, and DES group had one case of sudden death for acute left heart failure, one case of recurrent angina, and one case of subacute stent thrombosis. Conclusion： DES for the treatment of STEMI has good security and lower occurrence rate of the postoperative MAACE incidence compared with BMS.