| 几种药物对吗啡相关的条件位置偏好影响的研究进展 |
| |
| 引用本文： | 潘姿娇,王建红,何敏.几种药物对吗啡相关的条件位置偏好影响的研究进展[J].生物磁学,2014(1):187-189. |
| |
| 作者姓名： | 潘姿娇 王建红 何敏 |
| |
| 作者单位： | [1]昆明医科大学生理系,云南昆明650031 [2]中国科学院昆明动物研究所灵长类认知实验室动物模型和人类疾病机理重点实验室,云南昆明650223 |
| |
| 基金项目： | 国家自然科学基金项目（31271168） |
| |
| 摘 要： | 条件化位置偏好（conditionedplacepreference，CPP），常用于研究药物成瘾的相关记忆。这里主要综述了一些药物对CPP的影响。神经肽S，神经肽FF，肌肽，孤啡肽，α-2受体激动剂，L-左旋千金藤啶碱，东莨菪碱，丙戊酸钠，巴氯芬对吗啡CPP有抑制效应；聚肌胞苷酸，氟伏沙明和金刚烷胺能增强吗啡CPP；阿坎酸能抑制乙醇和某些类别的滥用药物的条件化奖赏效应，但不影响吗啡引起的条件化奖赏效应；褪黑激素逆转吗啡诱导的奖赏效应；人重组干扰素-α导致吗啡CPP的恢复。
|
| 关 键 词： | 药物 吗啡 条件位置偏好 |
Research Progress of Drugs Related to Morphine Conditioned Place Preference＊ |
| |
| PAN Zi-jiaoI,WANG Jian-hong,HE Min.Research Progress of Drugs Related to Morphine Conditioned Place Preference＊[J].Biomagnetism,2014(1):187-189. |
| |
| Authors: | PAN Zi-jiaoI WANG Jian-hong HE Min |
| |
| Institution: | 1 Physiology department of Kunming Medical College, Kunming, Yunnan, 650031, China; 2 Laboratory ofPrimate Neuroscicnce Research and Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, the Chinese Academy of Science, Kunming , Yunnan, 650223, China) |
| |
| Abstract: | Conditioned place preference （cpp）was used in studying drug addiction related to memory. Here we mainly reviewed the effect of some drugs on cpp. Neuropeptide S and neuropeptide FF, camosine, opioid peptide noeiceptin, α-2 agonists, l-stepholidine, scopolamine, valproate sodium, baelofen impaired morphine cpp; polyinosinic-polycytidylic acid, fluvoxamine and amantadine anti enha- nced morphine cpp; anti-relapse compound acamprosate suppressed ethanol and certain categories of drug abuse, but had no effect on morphine cpp; elatonin melatonic reversed of morphine-induced the rewarding effect; recombinant human interferon-α can retrieved morphine epp. |
| |
| Keywords: | Medicine Morphine Condition place preference |
| 本文献已被 维普 等数据库收录！ |
|
