多囊卵巢综合征伴胰岛素抵抗的研究进展

多囊卵巢综合征（polycystic ovary syndrome，PCOS）是国内外研究者、医患人员非常关心的育龄期妇女常见的内分泌代谢疾病，其主要表现为闭经、月经量减少、肥胖、不孕、体多毛等。多数伴有胰岛素抵抗（insulin resistance，IR）的发生，胰岛素抵抗（insulin resistance，IR）是指正常水平的胰岛素促进葡萄糖摄取及利用能力下降，机体各组织、器官代偿性分泌胰岛素以维持机体血糖稳定的一种代谢状态。近年来的研究不断证实PCOS患者2型糖尿病、血脂代谢紊乱及代谢综合征（metabolicsyndrome，MS）等并发症的发病率明显增高。运动能够改善2型糖尿病患者胰岛素抵抗的说法已经得到了共识，其分子机制也逐渐分明。PCOS患者胰岛素抵抗的研究目前仍处于进一步探讨阶段，但是经过近几年的努力已经有了新的进展，若在PCOS胰岛素抵抗患者的治疗过程中给予一定的运动干预，相信一定能够有新的突破。本文就PCOS患者胰岛素抵抗研究的机制、诊断及治疗方法的新进展简单做一综述。

Polycystic Ovary Syndrome with Insulin Resistance Research Progress

Polycystic ovary syndrome, the researchers at home and abroad, medical researchers are concerned about the childbearing age women of common endocrine metabolic disease. The main performance for amenorrhea, menstrual quantity decreases, obesity, infertility, hairy body, at. It＇s most associated with insulin resistance. Insulin resistance（insulin resistance, 1R） refers to the normal levels of insulin to promote glucose uptake and utilization ability to drop, the body＇s tissues and organs compensatory sex secretion of insulin to keep blood sugar stable body metabolic status. Recent studies have confirmed that the PCOS patients with type 2 diabetes, blood lipid metabolic disorder and metabolic syndrome （metabolicsyndrome,MS） the incidence of complications such as increased obviously. Exercise can improve insulin resistance in patients with type 2 diabetes that have got the consensus and its molecular mechanism is also gradually clear. Although the study of insulin resistance in PCOS patients are still in the stage of timber discussion, but through the efforts of recent years have made new progress. If certain sports intervention can be offered in the treatment of patients with PCOS insulin resistance in the process, it is believed that a new breakthrough can be achieved. This review is to review, the mechanism of insulin resistance in PCOS patients research, diagnosis and treatment progress of simple.