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围产儿出生缺陷分析及干预措施
引用本文:冯云,刘智昱,王淑媛,洪春辉,熊伟.围产儿出生缺陷分析及干预措施[J].生物磁学,2013(24):4746-4751.
作者姓名:冯云  刘智昱  王淑媛  洪春辉  熊伟
作者单位:[1]湘潭市妇幼保健院湖南湘潭411104 [2]湖南省妇幼保健院湖南长沙410008
基金项目:2012年度湘潭市第一批市级科技计划项目(SF20121008)
摘    要:摘要目的:掌握围产儿出生缺陷的发生情况,探讨引起围产儿出生缺陷的相关因素,为制订及完善出生缺陷预防对策及干预措施提供科学依据。方法:按照全国出生缺陷监测中心制定的监测方案,对2010年10月1日~2011年9月30日在湘潭市县级及以上医疗保健机构住院分娩的围生儿出生缺陷监测资料进行分析。结果:5年出生缺陷的平均发生率为93.30/万,出生缺陷的发生率无明显趋势(x2=0.114,P=0.736)乡村的出生缺陷发生率明显高于城镇(X2=24.638,P〈O.001),男性围产儿的出生缺陷发生率显著高于女性(XZ=6.693,P=0.010),出生缺陷的发生率与季节无关(x2=3.852,P=0.278),出生缺陷的围产儿死亡率大大高于非出生缺陷)L(X2=2904.583,P〈0.001),先天性心脏病、肢体畸形(并指/趾、多指/趾、肢体短缩、马蹄内翻足)、唇裂及唇腭裂是高发的出生缺陷。结论:减少出生缺陷的发生是一项长期工程,需要采取综合措施,从各个环节入手,以预防为主,加强优生优育健康教育,落实婚前及围产期保健,推行新生儿疾病筛查,可有效降低出生缺陷的发病率,提高出生人口素质。

关 键 词:围产儿  出生缺陷  相关因素  干预措施

Analysis of the Perinatal Birth Defects and Intervention Methods
FENG Yun,LIU Zhi-yu,WANG Shu-yuan,HONG Chun-hui,XIONG Wei.Analysis of the Perinatal Birth Defects and Intervention Methods[J].Biomagnetism,2013(24):4746-4751.
Authors:FENG Yun  LIU Zhi-yu  WANG Shu-yuan  HONG Chun-hui  XIONG Wei
Institution:1 Xiangtan Maternity and Child Healthcare Hospital, Hunan, Xiangtan, 411104, China; 2 Maternal and Child Health Hospital of Hunan Province, Hunan, Changsha, 410008, China)
Abstract:Objective: To master the occurrence of birth defects and investigate the cause of birth defects related factors to explore perfect birth defects prevention methods. Methods: Monitoring program developed in accordance with the National Birth Defects Monitoring Center from October 1, 2010 to September 30, 2011, in Xiangtan City, the county level and above health care organizations hospital delivery, perinatal child birth defects monitoring data analysis. Results: 5-year birth defects average rate of 93.30 / million, The rate of birth defects in no obvious trend (XZ=-0.114, P=0.736), In rural areas the incidence of birth defects is higher than in urban(XZ=-24. 638,P〈0.001). and the incidence of birth defects of boys is higher than girls (XZ-=-6.693, P=0.010).The incidence of birth defects there is no seasonal trends (XZ=-3.852, P=0.278), The perinatal mortality rate of birth defects in children is much higher than the non-birth defects in children(XZ=2904.583 ,P〈0.001). The following is the high incidence of several birth defects as Congenital heart disease(CHD), limb deformities(And refers to the / toe, multi-finger / toe, Limb shortening, club foot), Cleft lip, cleft lip and palate. Conehtsion: Reducing the incidence of birth defects is a long-term project, and it is necessary to adopt comprehensive methods from all aspects of starting, prevention, to strengthen prenatal and postnatal care health education, the implementation of pre-marital and perinatal care, the implementation of neonatal screening to effectively reduce the incidence of birth defects, and improve the quality of the population.
Keywords:Perinatal  Birth defect  Correlative factor  Intervention method
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