糖尿病患者外科手术麻醉的相关多态性及Logistic分析

目的：研究与探讨糖尿病患者外科手术麻醉的安全性和有效性。方法：糖尿病外科手术患堵262例，采用腰一硬联合麻醉146例，全身麻醉116例。结果：表明腰一硬联合麻醉组在术中血糖均值水平、胰岛素的平均使用剂量均少于全身麻醉组，有统计学意义（p〈0．05）。腰．硬联合麻醉组麻醉后空腹血糖、餐后血糖、糖化血红蛋白水平增高幅度均小于全身麻醉组，（P〈0．05）。通过用Logistic回归方程分析影响糖尿病患者麻醉效果的因素除性别无显著相关性，年龄、糖尿病病程、吸烟、饮酒、体重指数均与麻醉效果有高度相关性（正相关）。结论：糖尿病手术患者采用腰．硬联合麻醉效果较好。

Related Polymorphism and Logistic Analysis of Surgical Anesthesia in Diabetes Patients

Objective： To study and investigate the safety and effectiveness of different ways of anesthesia on the diabetes patients undergoing surgery. Methods： A total of 262 cases of surgical patients with diabetes were selected.Among the patients, 146 cases were performed waist and epidural anesthesia and 116 cases, general anesthesia. Results： The perioperative blood sugar level and mean insulin doses were less in combined spinal and epidural anesthesia group than in general anesthesia group, with statistical significance （P〈0.05）. In combined spinal and epidural anesthesia group, the increased extent of fasting and postprandial blood glucose, glycated hemoglobin levels were less than those in general anesthesia group （P〈0.05）. Through Logistic regression analysis, factors such as age, smoking, drinking and body mass index, except for gender, were highly correlated with the anesthesia effect on diabetes patients （positive）. Conclusion： Waist and epidural anesthesia is better for patients with diabetes.