首页 | 本学科首页   官方微博 | 高级检索  
   检索      

活络效灵丹抗炎镇痛作用的实验研究
引用本文:付通攀,但春梅,郑焱江,王瑞森.活络效灵丹抗炎镇痛作用的实验研究[J].生物磁学,2011(23):4548-4551.
作者姓名:付通攀  但春梅  郑焱江  王瑞森
作者单位:成都中医药大学药学院,四川成都611130
摘    要:目的:研究活络效灵丹的抗炎、镇痛、消肿等药理作用,为该药的临床研究提供基础。方法:用二甲苯致小鼠耳肿胀法和角又莱胶致大鼠足肿胀法研究抗炎作用,用热板法和扭体法研究镇痛作用。结果:活络效灵丹能较好地抑制二甲苯引起的小鼠耳廓炎性肿胀和大鼠甲醛致足跖肿胀,能显著提高热板试验小鼠的痛阈,有效抑制冰醋酸引起的小鼠扭体反应次数。结论:活络效灵丹具有良好的抗炎、镇痛、消肿等作用。

关 键 词:活络效灵丹  抗炎作用  镇痛作用

Anti-inflammatory and Analgesic Effects of Huoluoxiaoling Pills
FU Tong-pan,DAN Chun-mei,ZHENG Yan-jiang,WANG Rui-sen.Anti-inflammatory and Analgesic Effects of Huoluoxiaoling Pills[J].Biomagnetism,2011(23):4548-4551.
Authors:FU Tong-pan  DAN Chun-mei  ZHENG Yan-jiang  WANG Rui-sen
Institution:(College of Pharmaceutical Science, Chengdu University of TCM, Chengdu 611130, China)
Abstract:Objective: To study the anti-inflammatory, analgesic and edema-reducing effects of Huoluoxiaoling Pills for the clinical research. Methods: The inflammatory reaction model of mouse ear edema engendered by overlaying the dimethvlbenzene on the auricle and rat paw swelling induced by injecting carrageenin to the toes, pain produced by injecting the glacial acetic acid to abdomen in mouse and hot plate. Results: Huoluoxiaoling Pills could inhibit ear inflammation induced by xylene in mice and paw swelling induced by form formaldehyde in rats. It was demonstrated that Huoluoxiaoling Pills had anti-inflammatory effects. Analgesic tests showed that Huoluoxiaoling Pills could significantly improve the pain threshold of mice, and effectively reduce writhing response frequency induced by acetic acid. Conclusion: Huoluoxiaoling Pills have anti-inflammatory, analgesic and edema-reducing effect.
Keywords:Huoluoxiaoling Pills  Anti-inflammatory Effect  Analgesic Effect
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号