高通量血液透析对尿毒症患者营养状况的影响

目的：探讨高通量血液透析对尿毒症患者营养状况的影响。方法：自身对照研究将38例维持性低通量血液透析患者转换为高通量血液透析（HPD）,HPD组使用日本旭化成APS-15u高通量透析器6个月,分别采用改良主观全面营养评估（MQSGA）及各项客观营养指标进行相关性分析。结果：经转换为高通量血液透析后主观全面营养评估较使用低通量血液透析有显著性差异;营养相关指标血清白蛋白（ALB）、血红蛋白较前有明显提高,差异有显著性（P〈0.05）;胆固醇较前相比无明显差异。结论：高通量血液透析能有效改善维持性透析患者的营养状况。

Effect of High-flux Hemodialysis on Nutritional Status of Uremic Patients

Objective： To study the effect of high-flux hemodialysis on nutritional status of uremic patients. Methods： Through its own control study, 38 patients with maintaining low-flux hemodialysis were transformed into high-flux hemodialysis. The patients in the high-flux hemodialysis group were treated with high-flux APS-15U dialyzer for six months,who were correlatively analysed by means of improved subjective thorough nutrient evaluation （MQSGA） and the various objective nutrition indexes respectively. Results： The levels of serum albumin and hemoglobin of the patients in the high-flux hemodialysis group were significantly increased compared with the low-flux hemodialysis group,with significant difference （P0.05） ; but no significant difference in the levels of cholesterol. Conclusions： The high-flux hemodialysis can effectively improve the nutritional status of maintaining dialysis patients.